Postdoctoral Position (Bioinformatics) | V973

Organisation/Company: Centre for Genomic RegulationResearch Field: OtherResearcher Profile: First Stage Researcher (R1), Recognised Researcher (R2)Positions: Postdoc PositionsCountry: SpainApplication Deadline: 15 Sep 2024 - 23:59 (Europe/Madrid)Type of Contract: TemporaryJob Status: Full-timeHours Per Week: 40Offer Starting Date: 4 Nov 2024Is the job funded through the EU Research Framework Programme? Other EU programmeReference Number: MICIU/AEI /10.13039/501100011033 y por el FSE+Is the Job related to staff position within a Research Infrastructure? NoOffer DescriptionThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated, and creative scientific team supported by a flexible and efficient administration and high-end innovative technologies.We are seeking a postdoctoral researcher to develop a project focused on understanding whether the nuclear localization of metabolic enzymes can be used to predict cancer stage, grade, and response to therapy. The selected candidate will analyse mass spectrometry (MS) data to determine the enrichment of metabolic enzymes in the chromatin compartment. Such data will be validated with immunohistochemistry and immunofluorescence (with the help of a technician), and the selected candidate will develop a pipeline for image analysis and integration of different markers together with subcellular localization of selected metabolic enzymes. The goal of this project is to develop novel guidelines for patient stratification based on the subcellular localization of enzymes.About the labOur laboratory specializes in high-throughput image analysis, subcellular proteomics, transcriptomics, genetic screening, bioinformatics, and cell and molecular biology techniques. We are a group of about 10 people from different cultures and countries. We are part of the genome biology department at the CRG, and we aim to understand why metabolic enzymes localize to the nuclear environment and participate in specific chromatin functions.
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