Description
Celtarys Research (www.celtarys.com), a newly created startup based in Santiago de Compostela (Spain), which develops and commercializes fluorescence-
based innovative chemical tools to improve drug discovery, is looking for a PhD with expertise in Medicinal Chemistry.
She / He will be responsible for the conceptualization, design and execution of internal development projects, funded projects and custom development of
fluorescent probes through the application of Celtarys Technology.
Requirements : Requirements
Requirements
A PhD in Medicinal Chemistry with >
4 years' experience as post doc.
Extensive and accreditated experience in :
Organic synthesis : full autonomy in design and realization of multipsteo synthesis (also more than 6-7 steps) for the obtention of complex molecular structure with specific restrictions in terms of stability (such as fluorophores, biomolecules derivatives, etc.);
Strong and wide knowledge of biomolecules and small molecules purification and characterization approaches;
Independent design of new molecules able to interact with specific targets of interest;
Deep understanding of the biological data related to the compounds developed to incorporate them into new designs and / or potential refinement of molecular probes leading to successful experimental outcomes;
Understanding of molecule / target interaction principles and modes;
Knowledge of medicinal chemistry basis and approaches to modify molecules structures to improve their bioactivity;
Strong independence, problem solving, troubleshooting skills and proven ability to lead research projects;
Responsible and goal-oriented professional, able to integrate into a multidiciscplinary team and work in a competitive environment, dealing with multiple projects and client deadlines.
Fluent in English
Experience in the field of fluorescent probes development is a plus.
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