(Ocq116) - Ylt-690 - Two Phd Positions In Erc-Funded Project Talkingphages. Decoding Communicat[...]

Two 4-year PhD positions are available in the Macromolecular Crystallography Unit headed by Prof. Alberto Marina at the Institute of Biomedicine of Valencia (CSIC), Valencia, Spain. Funded by the ERC collaborative project TakingPhages, we will decipher and establish the molecular basis of the Arbitrium system, a novel communication mechanism of bacteriophages and other mobile genetic elements that confers social attributes.By providing knowledge about the molecular mechanism of Arbitrium and its diversity, we aim to understand how this microbial communication mechanism shapes the diversity of mobile genetic elements, the interactions among mobile genetic elements, and its role in bacterial ecology and evolution. The experimental approach will consist of a broad range of structural, biochemical, and biophysical techniques in bacterial and mobile genetics models. We offer an international, stimulating, and well-funded working project in a multidisciplinary environment with our collaborators headed by Prof. José R. Penadés (Imperial College London, UK) and Prof. Avigdor Eldar (Tel Aviv University, Israel).Recent Related Publications:Zamora-Caballero et al. (2024) Nat Microbiol. doi:10.1038/s41564-023-01550-4Brady A et al (2023) Cell Host Microbe. doi:10.1016/j.Chom.2023.11.003Gallego Del Sol et al (2022), Nat Commun. doi:10.1038/s41467-022-31144-3Where to ApplyField: Biological sciences » BiologyEducation Level: Master Degree or equivalentResearch Fields: Biological sciences » Other, Chemistry » Biochemistry, Physics » BiophysicsSkills/QualificationsPhD students should have (or be close to completing) a Master's degree in Molecular Life Sciences, ideally with a focus on Structural Biochemistry or Molecular Microbiology. Previous experience in protein production, purification, and characterization will be positively evaluated but is not a necessary requirement. We are seeking candidates who are highly self-motivated and committed, able to work both independently and in a team environment. We offer a 4-year predoctoral contract.LanguagesENGLISH Level: GoodAdditional InformationBenefits:High-profile research project, fully financed by European GrantWork in collaboration with international laboratories with the possibility of internshipsFunding available for four years with the possibility of extension to a postdoctoral contract upon completion of the PhD
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