(Hcg578) Associate Scientist, Lentivirus Downstream Process Development

Detalles de la oferta

.Johnson & Johnson is currently recruiting for an Associate Scientist, Lentivirus Downstream Process Development to be based in Spring House, PA. At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.Jnj.Com/ .Within Research & Development, the Discovery, Product Development & Supply (DPDS) organization is responsible for the development, clinical supply, marketed product support, and life cycle management of Biotherapeutics. Within DPDS, the API Cell and Gene group supports product development of novel cell and gene therapies for unmet medical needs.Primary Responsibilities: Conduct small scale lentiviral vector production process development using material from mammalian cell culture.Purification techniques will include depth filtration, affinity and/or Ion exchange (IEX) chromatography, and tangential flow filtration (TFF), sterile filtration etc.Perform a range of viral vector process characterization studies to support process performance qualification (PPQ) and regulatory filing.Assist the process technical transfer to manufacturing site as needed.Design, execute, analyze data and draft reports for studies.Stay current with relevant literature and evaluate new emerging technologies in viral vector production, incorporating them into processes as appropriate.The candidate is expected to work in a team environment as well as individually to meet project timeline and objective.Ensure data integrity through accurate and timely data capture/entry into appropriate electronic systems.Qualifications Required: B.S. or master's degree in biology, Biochemistry, Bioprocess Engineering, Virology, or a related scientific field is required.Minimum 1 year of experience doing protein and/or viral vector purification is required.Strong interpersonal skills, with the ability to closely collaborate with scientists and external teams is required.Preferred: Lentivirus experience is preferred.Hands-on experience with ÄKTA FPLC purification systems is highly preferred.Hands-on experience with TFF systems is highly preferred.Experience working with remote teams is preferred.Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability


Salario Nominal: A convenir

Fuente: Jobtome_Ppc

Requisitos

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