.Descripción : The Barcelona Institute for Global Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy, and education.
ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level.
Research is organized in five programs: Climate, Air Pollution, Nature and Urban Health; Environment and Health over the Lifecourse; Global Viral and Bacterial Infections; Malaria and Neglected Parasitic Diseases; and Maternal Child and Reproductive Health.
ISGlobal is accredited with the Severo Ochoa distinction, a seal of excellence of the Spanish Science Ministry.Lugar : BarcelonaWHAT WE ARE LOOKING FOR : ISGlobal is seeking a Technician who is interested in taking over and managing activities of the project: MOLECULAR INSIGHTS OF CRYPTIC ERYTHROCYTIC INFECTIONS IN THE HUMAN MALARIA CAUSED BY PLASMODIUM VIVAX (CRYPTICVIVAX).
The overall project goal is to unveil molecular insights of the newly described cryptic erythrocytic infections of this species using novel transformative technologies of humanized mouse models and organs-on-a-chip.TRAINING AND EXPERIENCE / QUALIFICATIONS : Laboratory experience Experience in working with extracellular vesicles In vitro culture experience Lab-chip experience Molecular and cellular biology techniques KEY RESPONSIBILITIES :Isolation and purification of extracellular vesicles from plasma and in vitro culture.
Conducting experiments in microfluidic devices.
Experience in this area is a pre-requisite.
Help in the analysis of humanized mice.
SPECIFIC DUTIES :Extracellular vesicles: isolation, purification, characterization through different technologies such as size-exclusion chromatography, immunocapture, FACs analysis, Western blot, nanoparticle tracking analysis.
Cell and parasite in vitro cultures.
Organ-on-a-chip: help with 3D seeding, 3D microcultures, imaging.
Analysis of the degree of human chimerism in humanized mouse models: qRT-PCR, IFAs, phenotypical FACs analysis.
AUXILIAR TASK : This job description reflects the present requirements of the post but may evolve at any time in the future as duties and responsibilities change and/or develop providing there is appropriate consultation with the post-holder.SKILLS :Teamwork.
Problem resolution.
Learning capacity.
The post holder will adhere to ISGlobal principles contained in People management policy, including Equity, diversity, and health safety.
The post holder will respect, and be accountable to ensure ISGlobal policies and procedures.CONDITIONS :Duration: 6 months Starting date: Dec 2024 Contract: Full time Salary Range: According to ISGlobal salary scale HOW TO APPLY : Applications will be accepted until 17.00 CET of the closing date