Work Schedule: Standard Office Hours (40/wk) Environmental Conditions: Office Job Description: At Thermo Fisher Scientific, you'll discover meaningful work that makes a positive impact on a global scale.
Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner, and safer.
We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development, and delivery of life-changing therapies.
Our work spans laboratory, digital, and decentralized clinical trial services.
Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.
Location/Division Specific Information: Clinical pharmacology provides the support vital to elucidate the pharmacokinetics and PK/PD relationships in support of our client's drug development efforts.
The Principal Pharmacometrician position is a "hands-on" position that provides both PK consultation and pharmacokinetic analyses.
In addition to leading their own projects, the Principal Pharmacometrician will work with our Clinical Pharmacology team to assist our clients in the design, analysis, and interpretation of PK, PK/PD, and population PK studies.
The ideal candidates will have the experience, insight, and skills necessary to provide interpretation of complex data and will be able to present this interpretation in a format and style that is compatible with client and regulatory requirements.
Discover Impactful Work: The Principal Pharmacometrician role is responsible for overseeing the design, analysis, interpretation, and implementation of modeling and simulation within the clinical pharmacology team.
Keys to Success: Education: Ph.D. or PharmD in relevant discipline (mathematics, statistics, pharmacokinetics, pharmaceutical sciences, bioengineering, etc.
), with an emphasis on clinical pharmacokinetics.
Experience: 5+ years in the Pharmaceutical or CRO Industry.
Must have experience with pharmacokinetic, medical, pharmaceutical, and research concepts.
Experience required in pharmacokinetic analysis and modeling with strong theoretical background; should have a proven record of accomplishments and publications.
Knowledge, Skills, Abilities: Must have experience and be proficient as a pharmacokinetic modeler using R and NONMEM software (familiarity with other modeling packages would be advantageous: Phoenix NLME, Simcyp, Gastroplus, Monolix, etc.).
Strong quantitative skills to develop models with nonlinear behavior, mechanistic or semi-mechanistic components, including must have dose-response modeling experience, QTc analysis, CAR-T analysis, etc.
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