Proyecto de Generación de Conocimiento 2023 by the Spanish Ministry of Science and Innovation
Introduction to the vacant position: The Spatial Biotechnology Group is looking for a talented and highly motivated Early Stage Researcher (PhD student) to develop his/her PhD thesis project on the development of experimental and computational approaches to study clonal behaviors in tumors. The candidate will use these approaches to carry out a PhD focused on molecular mechanisms and cellular organization of the tumor microenvironment. The candidate will use cutting-edge multiplexed tissue technologies, in vitro co-culture systems, engineered tumors, high-resolution imaging, assay automation, and computational tools for deconstruction of molecular and cellular spatial patterns in cells and tissues.
This fellowship is associated with the Generación de Conocimiento research project "Development of new multi-omic spatial methods to profile clonal events in cancer", funded by the Spanish Ministry of Science and Innovation.
Main tasks and responsibilities: Investigate molecular mechanisms and cellular organization:Design and execute experiments to study clonal behaviors in tumors.Utilize cutting-edge technologies to probe the tumor microenvironment. Work with multiplexed tissue technologies, in vitro co-culture systems, and engineered tumors.Analyze molecular interactions and spatial arrangements of cells within tumors.Deconstruct spatial patterns:Processing of fluorescence, sequencing, and mass spectrometry imaging data.Implement and refine computational methods for analyzing spatial patterns in cells and tissues.Identify key molecular and cellular patterns associated with tumor behavior.Disseminate research findings:Prepare and present research findings at lab meetings and scientific conferences.Publish research results in peer-reviewed journals.Contribute to the scientific community through active participation and collaboration.Requirements for candidates: Essential: Degree in bioinformatics, chemistry, physics, biotechnology, biomedicine, or related fields.Experience with molecular biology techniques (e.g., PCR, cloning), immunohistochemistry, in situ hybridization and cell culture.Experience programming and scripting in Python and/or R.Candidates should be ready to enter an official doctoral programme in December 2024 (under Spanish Law). By this time, they must have obtained a university degree and a master's degree; or must hold an official university qualification from a country of the European Higher Education Area with a minimum of 300 ECTS of official university studies, of which at least 60 are at master's level. Candidates who expect to be awarded with such degrees by October 2024 are eligible to apply.Candidates must have a strong commitment to scientific research and an excellent academic record.Candidates must have a good working knowledge of English.Candidates must not yet have been awarded a doctoral degree.Candidates must not have held a Ph.D. contract exceeding twelve months by the beginning of the fellowship (December 2024 to January 2025).Good skills in communication, teamwork, proactivity, characterization, integrity, time management, critical and analytical thinking, precision, and focus.Willingness to work in a highly multidisciplinary environment.Desirable: Previous experience with spatial tissue biology technologies.Previous experience in image analysis.We Offer: Number of available positions: 1Predoctoral researcher contract: 4 yearsStarting date: As of December 1st, 2024 (to be confirmed, based on the resolution of the call Proyectos de Generación de Conocimiento 2023 by the Spanish Ministry of Science and Innovation).How to apply: Until October 16th an online application form is available through IBEC dedicated site: https://careers.ibecbarcelona.eu/ Only those applications submitted before the deadline will be evaluated.
Reference: FPI_XR
If you have any further questions regarding your application, please contact us at ****** IBEC's Commitment on equal opportunity: Our strength and excellence as an international transdisciplinary Research Institute are based on diversity. Being an equal opportunity employer, we are committed to diversity and inclusion, so that we support employees irrespective of their gender, nationality, religion, disabilities, age, sexual identity or cultural and socioeconomic background.
IBEC, as a signatory of the San Francisco Declaration on Research Assessment (DORA), will consider, especially for early-stage investigators, much more the scientific content of research outputs, than publication metrics or the identity of the journal in which it were published.
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Personal data will be processed solely for the purposes of the selection process.
Who we are? The Institute for Bioengineering of Catalonia, IBEC is an interdisciplinary research center focused on Bioengineering and Nanomedicine based in Barcelona. IBEC is one of the top research institutions named as a Severo Ochoa Research Centre by the Ministry of Science, Universities and Innovation, which recognizes excellence at the highest international level in terms of research, training, human resources, outreach and technology transfer.
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