Organisation/Company BIODONOSTIA HEALTH RESEARCH INSTITUTE
Research Field: Biological sciences
Researcher Profile: First Stage Researcher (R1)
Positions: Master Positions
Country: Spain
Application Deadline: 30 Nov 2024 - 23:59 (Europe/Madrid)
Type of Contract: Temporary
Job Status: Full-time
Hours Per Week: 35
Offer Starting Date: 4 Nov 2024
Is the job funded through the EU Research Framework Programme? Horizon Europe - ERC
Is the Job related to staff position within a Research Infrastructure? No
Offer Description
PhD project in the field of Biotechnology, Chemistry, Biochemistry, Biomedical Eng., Chemical Eng., Materials Science or related
The Cipitria Lab – Bioengineering in Regeneration and Cancer at Biogipuzkoa Health Research Institute, San Sebastián-Donostia, Spain (https://cipitrialab.com) is looking for a doctoral researcher. In our group, we aim to understand how biophysical and biochemical properties of native extracellular matrix and synthetic biomaterials guide cell response in regeneration, cancer dormancy and bone metastasis. We are located within the structure University Hospital Donostia-Onkologikoa.
Funded by an ERC CoG grant (https://doi.org/10.3030/101123883), the main objective of DORMATRIX is to engineer breast cancer dormancy as a collective emergent phenomenon using biomaterials-based dormancy-on-a-chip devices. In this project, you will model in vitro breast cancer micro-units applying biophysical principles with novel biomaterials.
DUTIES AND RESPONSIBILITIES:
Apply biophysical principles with novel biomaterials to model in vitro breast cancer micro-units.
Hydrogel synthesis and development of microparticles with controlled physico-chemical properties.
Culturing breast cancer cells in controlled 2D and 3D microenvironments.
Monitoring breast cancer cell dynamics with advanced microscopy and time-lapse fluorescence life cell imaging.
Collaborate in additional projects and become an integral member of our team.
Participate in regular consortium meetings and larger consortium events.
Suggested reading:
Young et al, Science Advances 10, eadj0975 (2024).
Qualifications:
MSc in Biotechnology, Chemistry, Biochemistry, Biomedical engineering, Chemical engineering, Materials Science or similar.
Previous experience in a biomedical lab working on hydrogel fabrication and cell culture will be an asset.
Excellent ability to conduct experiments independently and collaboratively within our group.
Collaborative mindset and motivation to work in an international, interdisciplinary environment.
Strong organization skills, project management and proactive "getting things done" mentality.
Interest to learn and grow professionally in a young, dynamic and competitive lab.
Have a genuine excitement for science, innovation and creative thinking!
Good written and oral communication skills in English (Spanish is not required).
VALUABLE: Possession of a disability certificate equal or superior to 33% would be an asset.
TYPE OF CONTRACT (LEGAL REFERENCE): One year Trainee Predoctoral Researcher contract available, extendable to a maximum of 4 years (annual extensions).
WORK SCHEDULE: Full time
EXPECTED START DATE: December 2024-January 2025
ANNUAL GROSS SALARY: 20.808€ gross per year
The remuneration shall be based on the candidate's commitment and merit, as well as how suited they are for the role. The worker must comply with the operating rules set by the Biogipuzkoa Institute in terms of commitment, duties, working hours, leave entitlements, etc.
Eligibility criteria:
EXPERIENCE (75 POINTS)
PROVEN LANGUAGE SKILLS (10 POINTS)
OTHER DISTINCTIONS (5 POINTS)
CERTIFICATE VERIFYING A MINIMUM DISABILITY OF 33% (0-10 POINTS)
For the application, please send in a single PDF of maximum size 5 MB (i) a motivation letter describing your experience, research interests, expectations and preferred start date, (ii) your CV with a complete list of publications, (iii) transcript of university record and (iv) contact information for three references, to: ****** and ******, indicating "DORMATRIX - PhD" in the subject line . The position will remain open until filled.
BIOGIPUZKOA is committed to the principles of open, transparent and merit-based recruitment (OTM-R policy), in accordance with the requirements of the HRS4R seal established by European Commission.
As such, it takes responsibility for ensuring gender equality based on the goals established in the current Gender Equality Plan.
Once the evaluation and selection have been conducted, candidates may request information on their scores, as well as the score of the selected candidate.
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