Postdoctoral Scientist Biopharmaceutics – (PBPK modeling of Amorphous Solid Dispersions)Location: Beerse, BelgiumAt Johnson & Johnson, we believe health is everything.
Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.The J&J IM Discovery, Product Development, & Supply (DPDS) organization helps early career scientists gain the training and experience needed to further develop their careers while addressing the needs of global healthcare.
Postdocs work side-by-side with DPDS scientists on innovative research projects, learning the functional role of scientists in the pharmaceutical industry.We are seeking a talented Postdoctoral scientist to join our Pharmaceutical and Material Sciences (PMS) team, which is part of the global Pharmaceutical Product Development & Supply (PPDS) organization within J&J IM R&D to be based in Beerse, Antwerp, Belgium.The main objective of this 18-month Postdoc project is to develop novel PBPK capabilities that integrate insights gained from in vitro and preclinical experiments within existing PBPK frameworks to allow better predictions of the plasma concentration time profile of drugs formulated as amorphous solid dispersions.
Efforts will mainly focus on mathematical modeling of key in vitro biopharmaceutics experiments such as drug solubility and dissolution.Position Responsibilities:Interpretation of in vitro biopharmaceutical data on amorphous solid dispersions, including solubility, biorelevant dissolution, permeability, and solid state characteristics.Literature Review and incorporation of in vitro data into existing PBPK software.Development of novel PBPK methodologies.Authorship and publication of scientific reports.Qualifications:A PhD degree in Pharmaceutical Sciences, Chemical Engineering, Pharmaceutical Technology, Analytical Sciences, or a closely related field with relevant experience in biopharmaceutics.Demonstrated competency and experience in biopharmaceutics, formulation development, and/or characterization.Experience in PBPK modeling is highly preferred.Experience with biopharmaceutical in vitro techniques (e.G., solubility, dissolution, precipitation, solid state characterization, permeability).Experience in coding (e.G., R, Python, Matlab).Proven ability to transform drug delivery challenges into innovative ideas and practical solutions.Excellent oral and written communication skills in English.On-site presence required (Beerse, Antwerp area, Belgium).For more than 130 years, diversity, equity & inclusion (DEI) has been part of our cultural fabric at Johnson & Johnson.
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