.Offer DescriptionThe Childhood Cancer & Blood Disorders group at VHIR is composed of clinical, translational and basic researchers and has three laboratories (Sarcomas lab, Neural Tumors lab and Rare Anemia Disorders lab) and three research programs (Personalized Medicine, Clinical Trials Unit and Stem Cell & Advanced Therapies Hematological Malignancies & Cell Therapy).Pediatric cancer has specific features that define it as an entity that in the majority of cases is certainly different from adult tumors; i.E.
etiology, biology,response to treatment and prognosis are significantly different.
The implementation of multimodal treatments (i.E.
combinations of chemotherapies, radiotherapies, biological agents...) in the last 20 years has enabled the increase in patient survival around 80%.
Although the global survival of pediatric cancer is around 80%, patients with some types of tumors present a much lower survival.
Moreover, almost two-thirds of patients who survive suffer severe side effects due to the treatment.
Therefore, the development of therapies to treat 20% of patients who do not survive and to reduce toxicity of current treatments avoiding long-term side effects is extremely necessary.The main objective of Neural tumor laboratory is to implement the use of epigenetic therapies, that is, therapies against gene expression modulators that, in turn, regulate several genes, pathways or cellular processes, without affecting the DNA sequence.
The laboratory focuses on neuroblastoma, a pediatric solid tumor of the peripheral nervous system, and on pediatric brain tumor of the central nervous system pediatric such as ependymoma, medulloblastoma or high-grade glioma among others.Main Responsibilities and Duties: Full-time position: 40h/week.In vitro and In vivo drug screening and efficacy studies.Prepare presentation of results and communication/dissemination material.Participation in laboratory outreach activities.Requirements Research Field: Biological sciencesEducation Level: PhD or equivalentSkills/Qualifications Education and Qualifications:Required:Bachelor's Degree in Sciences (Biology, Biochemistry, Pharmacy, Biotechnology, Genetics, Medicine, etc.)
and MasterPhD in Cancer Biology.Desired:Good command of Spanish & English (C1/C2 level).Experience and Knowledge:Required:Experience in drug development projects.Desired:Good communication skills and good team playerInternational internship.Additional Information Benefits Labour Conditions:Starting date: February 2025Gross annual salary: Remuneration will depend on experience and skills.
Salary ranges are consistent with our Collective Agreement pay scale