FUNDACION PARA LA INVESTIGACION MEDICA APLICADA 09 Dec | FUNDACION PARA LA INVESTIGACION MEDICA APLICADA | Pamplona
The Fortes lab at CIMA (University of Navarra, Spain) is looking for a postdoctoral student with a molecular biology background and skills in RNA biology to investigate the interplay between DNA damage and functional non-coding RNAs.
The Fortes lab (https://cima.cun.es/en) aims to develop biotechnological tools based on natural long non-coding RNAs and derived microproteins or on artificial non-coding sequences. We work to deliver these novel RNA therapeutics into tumor cells with a special focus on hepatocellular carcinoma. We have a network of outstanding collaborators to expand our expertise from the bench to preclinical models and to the clinical setting.
Your role The successful candidate will work on a cutting-edge experimental research project that moves from single molecule studies performed in close collaboration (AFM, cryo-EM, magnetic tweezers, C-trap), and genetic evolution (SELEX) or identification of natural lncRNA mimics with novel high-throughput technology to cellular validations and preclinical models. The goal of the project is to contribute with exquisite technology with translation potential to the future understanding of the RNA code: the set of rules that link RNA sequence with structure and function.
The complete project involves a combination of molecular biology, biophysics, and structural biology. This project is in close collaboration with Fernando Pastor (also at CIMA), Oscar Llorca (CNIO, Madrid) and Fernando Moreno-Herrero (CNB, Madrid), and will involve regular communication and scientific exchange with the collaborators.
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