The Institute The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated, and creative scientific team supported by a flexible and efficient administration and by high-end and innovative technologies.
The Single Cell and Synthetic Genomics of Blood Formation lab (PI: Lars Velten) at CRG Barcelona is looking for a motivated computational or mixed computational-experimental postdoc to use synthetic enhancers, CRISPR screening, and computational approaches to unravel the logic of gene regulation in blood stem cell differentiation.
In your new role, you would:
Develop a project on gene regulation in the blood forming system.Analyze data from synthetic enhancer MPRA screens, single cell MPRA screens, and dual MPRA-CRISPR screens.Design experiments using these technologies and collaborate with an experienced technician to implement these experiments.Interact closely with both wetlab and computational scientists from the group.Serve as a senior member of the team and, down the road, co-supervisor of PhD students or technical staff.Whom would we like to hire? Professional experience Must Have You hold a PhD in a relevant field (computational biology, genomics, molecular biology, bioinformatics, biotechnology etc.).You have demonstrated your ability to lead a challenging research project.You have published at least one primary research paper during your PhD.You have strong experience in the analysis of non-standard genomics data (e.g. Perturb-Seq, CRISPR screens, Nanopore, custom RNA-seq protocols etc).Experience in both exploratory and formal data analysis.You have strong programming skills in R or Python.You embrace data-driven research and are willing to collaborate with computational biologists.Desirable but not required/Nice to have You have, in addition to your computational training, training in experimental work (e.g. cell culture, flow cytometry, cloning, library preparation etc.).A strong foundation in machine learning and statistics.You have experience with deep learning environments such as TensorFlow and PyTorch.Education and training A PhD in a relevant field (biochemistry, biomedicine, molecular biology, genetics, etc.).
Languages You are proficient in English.
Technical skills R and Python.
Competences Success-driven.Strong academic writing skills.Ability to work as part of a team.The Offer – Working Conditions Contract duration: technical and scientific activities contract, estimated 2 years.
Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
Target start date: January 2025 (flexible).
We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities.
We offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation, or gender identity.
Application Procedure All applications must include:
A motivation letter addressed to Dr. Lars Velten.Contact details of two referees.All applications must be addressed to Dr. Lars Velten and be submitted online through the "Apply" button below.
Deadline: Please submit your application by October 10, 2024.
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