The Institute The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries.
The CRG is composed of an interdisciplinary, motivated, and creative scientific team supported by a flexible and efficient administration and high-end innovative technologies.
In April 2021, the CRG received the renewal of the 'HR Excellence in Research' Award from the European Commission.
This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to align practices and procedures with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).
Please check out our Recruitment Policy.
The role The Single Cell Genomics of Tissue Regeneration lab (PI: Lars Velten) at CRG Barcelona is looking for a bioinformatics postdoc , with an interest in deep learning, gene regulation, single-cell genomics, and synthetic biology.
Your work would be part of the project "Artificial Intelligence for Synthetic Genomics of Blood," funded with a prestigious ERC Starting Grant.
A 45-second video summary of that grant is available online.
In your postdoc project, you would: Develop deep learning architectures to analyze data from large-scale genetic screens with single-cell readouts (CRISPR and MPRA screens).
Develop tools for designing maximally informative experiments.
Ultimately, design synthetic DNA to control gene expression in arbitrary cell states.
Interact closely with experimental biologists and design experiments with them.
Have a large degree of freedom to develop your project.
Serve as a senior member of the team and co-supervisor of PhD students.
About the lab The group is interdisciplinary and investigates the biology of hematopoietic stem cells using a combination of single-cell genomics, genetic screens, and computational biology.
It strives to develop novel genomic and bioinformatic tools to answer longstanding questions in the field, covering two main research lines: Gene regulation in healthy hematopoiesis.
The role of stem cells in blood cancer.
The lab, established in January 2020, currently consists of 5 members: a Bioinformatics PhD student, a bioinformatics postdoc, 2 biotechnology PhD students, and a technician.
It is funded by the Spanish and German governments as well as the European Commission.
Whom would we like to hire?
Professional experience Must Have: You embrace data-driven research and are willing to collaborate with experimental biologists.
You are willing to take a co-leadership role in a young team.
You have published at least one primary research paper during your PhD.
Desirable but not required/Nice to have: You have experience analyzing genomic data, e.g., single-cell genomic data, regulatory genomics, etc.
You have experience with package development in R or Python.
You have experience with statistical modeling, e.g., Hierarchical Bayesian Models.
If you have previous experience with deep learning and relevant libraries (e.g., TensorFlow, Pytorch, Pytorch Geometric, Pyro), it would be a big plus.
Education and training You have recently completed your PhD in bioinformatics, computer science, or a related field.
Languages You are proficient in English.
Technical skills You have excellent programming skills in Python and experience with relevant deep learning libraries.
Competences You are success-driven, have good academic writing skills, strong communication skills, and the ability to work as part of a team.
The Offer - Working Conditions Contract duration : Initially 2 years with the possibility of extension up to 5 years.
Estimated annual gross salary : Salary is commensurate with qualifications and consistent with our pay scales.
Target start date : As soon as possible.
We provide a highly stimulating environment with state-of-the-art infrastructures and unique professional career development opportunities.
To check out our training and development portfolio, please visit our website in the training section.
We offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation, or gender identity.
The CRG is committed to reconciling work and family life for its employees and offers an extended vacation period and the possibility to benefit from flexible working hours.
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