.VHIR-RRHH-FOR-003_vs02The Vall d'Hebron Research Institute (VHIR) is a public sector institution that promotes and develops the research, innovation and biosanitary teaching of the Vall d'Hebron University Hospital. Through the excellence of our research, we identify and apply new solutions to the health problems of society and we contribute to spreading them around the world.In April 2015, the Vall d'Hebron Research Institute (VHIR) obtained the recognition of the European Commission HR Excellence. This recognition proves that VHIR endorses the general principles of the European Charter for Researchers and a Code of Conduct for the Recruitment of Researchers (Charter & Code) .VHIR embraces Equality and Diversity. As reflected in our values, we work toward ensuring inclusion and equal opportunity in recruitment, hiring, training, and management for all staff within the organization, regardless of gender, civil status, family status, sexual orientation, gender identity and expression, religion, age, functional diversity or ethnicity.Master Graduate ResearcherTHERAPEUTICS AND INNOVATION IN NEUROPEDIATRICS AND OTHER PAEDIATRIC RARE DISEASES (TIN-RD) GROUPThe group aims to promote the implementation of advanced therapies and innovative therapies of high technological complexity in pediatric rare diseases, specifically in Neurological ultra-rare diseases that impact the motor development of children and adolescents. The group focuses on three main objectives: (1) to perform a precise genetic diagnosis of ultra-rare diseases causing disorders of motor development in childhood and adolescence; (2) to develop programsfor personalized medicine according to the clinical phenotype and genetic background of our patients; (3) to analyze digital and imaging biomarkers that predict best outcomes and select best candidates for the different therapies offered by the group.In this call, we offer a master graduate position to study predictors of efficacy in children with motor development disorders and dystonia treated with deep brain stimulation (DBS), a high technologically innovative therapy that has been implemented at Vall d'Hebron Pediatric Hospital since 2020. The aim of this project is to identify differences between DBS responders and non-responders in order to identify the best candidates for DBS.Main Responsibilities and Duties:Management of databases from DBS surgery and analysis of variables associated with DBS outcomes.Handling, processing and storage of biological samples and associated data.Routine and non-routine experiments which will include molecular analysis utilizing standard techniques (DNA and RNA extraction, PCR), and cell culture experiments.Collaborate with genetic studies and work on variant prioritization resources.Collaborate with administrative and laboratory management tasks.Labour Conditions:Full-time position: 40h/week.Starting date: January 2025.Gross annual salary: 26000€/year
