Grading: 4, 5 or 6 depending on experience and qualificationsAbout the job/teamThe Light Imaging Facility of the Epigenetics and Neurobiology Unit at EMBL Rome, Italy, is looking for an imaging expert who will participate in the activities of the facility as part of a collaborative international environment. The facility provides access to state-of-the-art imaging instruments, supports training and develops technology in collaboration with research groups and industry.Your roleIf you are passionate about making an impact in life science research, love staring at the scope for hours and debugging code in your spare time, have a service-oriented personality, and are motivated to develop technology for the wider community, we want to hear from you.Your responsibilities include:Carrying out work requests using tissue sample preparation methods (from basic IF/RNA FISH to spatial omics) followed by imaging and data analysisProficiency in the use of high-end microscopes and associated software, including Crest V3 spinning disk confocal microscope, Nikon AX/R scanning confocal microscope, Leica Thunder, Olympus VS200 slide scanner, Alpenglow open top light sheet systemContributing to the training of staff and students, ensuring safe operation and maintenance of our instrumentsDeveloping experimental and/or bioimage analysis protocols to support research projectsImplementing novel sample preparation protocols, analysis pipelines and imaging methodsContributing to the management of the facility, such as newsletters and antibody stocksEngaging in technology development projects (e.g., spatial omics or expansion microscopy) and ensuring their implementation in a facility settingYou have:MSc or PhD in Biology, Physics, Chemistry, Bioengineering or related subjectsAdvanced knowledge in light/fluorescence microscopyExperience in tissue or cell sample preparation methods (from basic IF and RNA visualization up to clearing techniques and expansion microscopy)Experience in at least one high-level programming language (e.g., Python)Proficiency with common bioimage analysis packages such as ImageJ, QuPath and NapariExcellent manual dexterity and organizational skillsPro-active attitude and hands-on approach to problem solvingExcellent communication skills, capable of explaining complex technical concepts clearly and effectively to colleagues and studentsTeamwork spirit and strong interpersonal skills with the highest ethical standardsFluency in written and spoken EnglishYou might have:Previous exposure to any one or several of these areas: super-resolution microscopy, fluorescence spectroscopy (FCS, FLIM, smFRET), fluidics, oligo design for RNA or DNA detectionKnowledge of multiplex imaging, spatial transcriptomics or bioinformatic analysis of -omics dataKnowledge of machine learning or deep learning for image analysisExperience in creating automation pipelines using tools like Arduino or FPGA'sWhy not? The European Molecular Biology Laboratory (EMBL) is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization with a highly collegial and family-friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including for your family.What else do I need to knowEMBL is one of the highest ranked scientific research organizations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK), Barcelona (Spain), and Rome (Italy). The Epigenetics and Neurobiology Unit at EMBL Rome studies various mammalian physiological phenomena from molecular to system levels using the mouse as a model system. We take advantage of institutional links with other EMBL sites.For more information or informal enquiries, please contact Alvaro Crevenna at ******
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