.The Global Market and Access Pricing team at AstraZeneca is establishing a new Centre of Excellence for HTA Statistics and Modelling Science at our global hub in Barcelona. This initiative aims to meet the needs of our expanding pipeline and the evolving external environment. We have exciting opportunities for experienced, applied HTA methodologists and health economic modellers to join our HTA and Modelling Science (HMS) team at either a Director or Lead Level. Our team covers a diverse range of therapeutic areas including Cardiovascular, Renal & Metabolism, Respiratory & Immunology, and Vaccines & Immune Therapies. As part of a multi-disciplinary group, including HTA statisticians, payer evidence experts, and market access specialists, you will help shape the payer environment by creating and delivering high-quality health economic models. These models will unlock the potential of our life-changing medicines for patients around the world. Accountabilities In this role, you will be responsible for implementing HTA methodology and applying your up-to-date hands-on modelling expertise to deliver high-quality, transparent, and fully validated health economic models that meet the requirements and expectations of HTA agencies. This will support patient access to our innovative medicines. With the growing use of HTA, including the upcoming Joint Clinical Assessment in Europe, you will play an important role in shaping our approach. By being at the forefront of methodology and innovation in the field, you will help position the Centre of Excellence for HTA Statistics and Modelling Science as a collaborative, reputable, and trusted organisation among HTA, policy, and academic stakeholders. Development of our people is of utmost importance to us. As part of our new Centre of Excellence, there will be opportunities to learn and further develop skills, as well as spread your knowledge and increase the overall capabilities in the organisation. For our Director role, you should have: Leadership and strategy setting on HTA modelling and simulation (including indirect treatment comparisons, utility analyses, survival analysis, treatment switching, and other advanced analytics used for HTA and wider market access) across different indications. Significant experience of hands-on modelling of patient level simulations, dynamic models, application of risk equations, parametric survival techniques, and Bayesian analyses, among others. Act as subject-matter expert to unlock modelling challenges and propose methodologically sound, pragmatic, and agile solutions to the team. Develop global standards, guidelines, best practice, and metrics within the team. Lead quality assurance on the implementation of accepted methods for modelling and full validation of health economic models prior to submissions to HTA bodies or scientific journals