.Science FacultyBarcelona, SpainEMBL Barcelona is a research unit focusing on Tissue Biology and Disease Modelling. We build tissues to understand them, either in vitro or in silico. We go beyond the molecular and cellular scale to ask questions such as: How do thousands of cells dynamically self-organise to create tissues and organs? How do new emergent properties arise at the tissue level? Why does this sometimes go wrong, causing disease? Can we engineer healthy or novel tissues in the laboratory? To tackle these grand challenges, our Unit combines an interdisciplinary mix of approaches, integrating molecular and cellular data with gene circuits, tissue engineering, multicellular omics, 3D mesoscopic imaging and computer modelling. Our current 7 research groups span work on organoids, in vitro vascular models, disease modelling, self-organisation and computational modelling of multicellular systems, with some of the groups combining both wet-lab and dry research.We are now seeking outstanding candidates to lead a new independent group in this area. We encourage applicants with a wide range of approaches. We are interested in candidates focussed on fundamental science questions about tissue dynamics and organisation using novel and exciting model systems combined with new tools and technologies (for example, but not limited to, improving the state-of-the-art in growing, controlling and engineering in vitro 3D tissues, spatial omics, network dynamics, advanced molecular biology, lineage-tracing, material engineering, microfluidics, etc.). Combining both experimental and computational research is a plus.Your roleYou will lead an independent research group to pursue highly ambitious and original research goals. You will be embedded in the multidisciplinary and collaborative environment of EMBL, which provides many opportunities for interaction with other research groups. EMBL generally appoints group leaders early in their career and provides a very supportive, collegial and family friendly environment in which to develop exciting, cutting-edge research. Significant core funding and very limited teaching obligations allow you undertake an ambitious, competitive research program.Closing date: 24 November 2024Contract duration: 5 years (renewable)Grading: 9Reference number: BCN00107You haveYou have an outstanding Ph.D. and post-doctoral record in a relevant scientific topic (in biology, physics, engineering or other relevant topic). You have strong experience in the field of 3D tissue biology and a track-record of exciting scientific achievements.You must have a novel research proposal which ideally combines:- Fundamental scientific questions – advancing the state of understanding of how 3D tissues grow, organise themselves or respond to disease (whether at a molecular, cellular or biomechanical level)