.AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development, and commercialization of prescription medicines for some of the world's most serious diseases. We are more than one of the world's leading pharmaceutical companies. AstraZeneca has a multifaceted environment that cultivates collaboration and innovation. We attract top minds, and we nurture and build talent.Within Hematology R&D, we are committed to advancing the science to deliver life-changing medicines to patients most in need. With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy, and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.Key Responsibilities: Accountable for the delivery of project according to quality, time, budgets, and resources.Build strategic and coordinated product development plans which are aligned with business objectives and are differentiated from competitor products.Accountable for the execution of the integrated product plan to agreed scope, timelines, and budgets.Lead and communicate the project development strategy at governance meetings, accountable for aligning with internal management and for communicating with external collaborators.Lead projects from preclinical Lead Optimization Investment Decision to clinical Proof of Concept (PoC).Responsible for all aspects of project strategy including preclinical, translational, clinical development, patient selection, regulatory, pediatric, intellectual property, CMC, and Asian development strategy.Development of the Target Product Profile, ensuring alignment with disease area strategy and late-stage development.Lead the Product Development Team (PDT) to effectively run/mitigate/communicate risk, make decisions, and handle conflict and change.Responsible for maintaining a high degree of PDT effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members.Ensure that there are robust processes, plans, and data to enable Governance Bodies to make investment decisions and prioritize projects across the portfolio.Minimum Qualifications: M.D. is required.A minimum of 7 years of relevant experience.Industry experience in drug development including experience in early and late phase drug development and regulatory knowledge.Strong knowledge and understanding of the Hematology Oncology therapeutic area with experience in diverse biological mechanisms.Broad understanding of the evolving clinical landscape in hematology/oncology.Lead the overall development of project strategy and be accountable for project plans, timelines, progress, and outcomes
