The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
We are seeking a talented computational expert with experience in next-generation sequencing data, particularly in single-cell transcriptomics and alternative splicing to cover for a leave for three months.
The primary goal of the job is to provide support to the projects carried out in the lab. The job will include (but is not restricted to):
Analysis of alternative splicing and gene expression using single-cell long-read sequencing data.Analysis of alternative splicing and gene expression using bulk RNA-seq.Identification of genome mutations in WGS data.About the lab
The Irimia lab is an international and multi-disciplinary team dually affiliated with UPF and CRG. It focuses primarily on elucidating the role of alternative splicing in vertebrate development and adult function, generally applying explicit evolutionary perspectives. Part of our work focuses on microexons in the nervous system and in endocrine pancreas, a splicing program that we have originally discovered and to which we have made key contributions. In our lab, we combine computational approaches (comparative bulk and single-cell transcriptomics and functional genomics) with experiments using in vitro and in vivo systems. In addition, we have recently started a strong collaboration with the BIMSB-MDC in Berlin, with the overarching goal of advancing single-cell transcriptomics with isoform resolution.
Whom would we like to hire?
Professional experience
Must Have:
Experience in next-generation sequencing analyses.
Ability to interact and collaborate with biologists.
Desirable but not required/Nice to have:
Experience in evolutionary analyses.
Experience with the generation of scientific visualizations with R.
Education and training
Hold a degree or PhD in disciplines such as Bioinformatics, Physics, Statistics, Biology, etc.
Languages
Technical skills
Programming in various languages (at least Python, Perl and/or R).
Competences
This job involves a lot of collaboration with other researchers; therefore, the candidate must enjoy working as part of a team.
Good organization skills.
The Offer – Working Conditions
Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales. We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.
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