Associate Principal Physician Scientist, Genomics

Detalles de la oferta

Location: Barcelona, Spain (On-site): We require 3 days working from the office and 2 days working from home.Are you ready to make a more meaningful impact on patients' lives around the globe? Here at AstraZeneca, we offer the opportunity to make a significant difference. Our science-driven approach allows us to transform lab-born breakthroughs into transformative medicines for the world's most complex diseases. With our ground-breaking pipeline, the future is bright. There's no better time to join our global, growing enterprise as we lead the way for healthcare and society.
What You'll do AstraZeneca's Centre for Genomics Research (CGR) is currently seeking a physician with a research background to join our dedicated team focused on the company-wide Genomics Initiative which includes the analysis of up to 2 million genomes. In this role, you will apply your medical knowledge to help interpret DNA and multi-omics research data from AstraZeneca's clinical trials and broad biobanks representing ancestry diverse populations. Furthermore, you will play a pivotal role in leading deep-phenotyping and cohort stratification efforts aimed to further improve opportunities of identifying and validating new therapeutic targets for drug development. You will also contribute to the harmonization of healthcare records collected from a diverse range of geographical regions, an essential activity for maintaining data consistency and reliability in our research efforts.
The successful candidate will work with leaders in human genomics delivering innovative science to genome analytics. You will also work closely with experts in translational science, drug discovery, pre-clinical modelling, and clinical development; thus, contributing to the broader objectives and success of the company-wide Genomics Initiative. This unique role requires an individual who is innovative, passionate about science, and can generate and lead original projects in a global R&D environment. The role will be primarily office-based, with some national and/or international travel to support projects, participate in team development meetings and attend conferences.
What you will be doing on daily basis? You will be... Coordinating analyses within AstraZeneca's Centre for Genomics ResearchApplying innovative quantitative genomic analyses to large-scale cohort studies to identify clinically relevant disease and response lociDeliver novel insights into the biology of disease, validation of new targets for medicines and the improvement of selection of patients for clinical trialsProviding detailed reports regarding the study design, analysis approach and research findings and presenting to study teamsChampion and lead the strategic direction of own projects and initiatives.Seek and apply best practices in processes, data analysis, and decision-making in leading project teams in a virtual environmentContribute to the overall success of the wider AstraZeneca BioPharmaceuticals R&D functions.Ensuring own work, and work of team, is compliant with Good Laboratory Practice, Safety, Health and Environment standards and all other internal AstraZeneca standards and external regulationsQualifications, Skills and Experience Required: Essential: Degree in MedicinePhD degree (or equivalent experience)Experience in large-scale data analysisAbility to communicate effectively with team members and non-experts, both verbally and through documentationHigh level understanding or interest in the potential of genomics to impact drug discoveryIn-depth understanding of medicine in its broadest contextDesire and willingness to 'Follow the Science' beyond core disease area of expertiseAbility to carry out duties under minimal supervisionExcellent interpersonal skills and willingness to work within a team in a quickly evolving environmentTrack record of peer-reviewed publications in high-level scientific journalsDesirable: Previous experience in a similar roleExperience harmonising clinical phenotype information and diverse health datasetsPragmatic experience with data querying and data exploration toolsExperience in case-control sequencing based statistical analysesExperience quantifying and interpreting the clinical relevance of rare variantsFamiliarity working on genomics studies involving one of AstraZeneca's core therapeutic areas (see: https://www.astrazeneca.com/our-therapy-areas.html)Clinical experience, now seeking entry to the biotech/pharmaceutical industryWhy AstraZeneca? Make a more meaningful impact to patients' lives around the globe At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.
Ready to embrace new and varied opportunities to develop and learn? Join us at AstraZeneca's Biopharmaceuticals R&D division! Apply now and be part of our mission to improve patient access to healthcare globally.
Where can I find out more? Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
Date Posted
25-Sep-2024
Closing Date
17-Oct-2024
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.


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